CHARACTERIZATION OF THE TUMOR IMMUNE MICROMILIEU AND ITS INTERFERENCE WITH OUTCOME AFTER CONCURRENT CHEMORADIATION IN PATIENTS WITH OROPHARYNGEAL CARCINOMAS

Background: Intra-tumoral CD8 + T-cell infiltration in squamous cell carcinoma of the head and neck (HNSCC) has previously been linked to the efficacy of cisplatin-based chemoradiation (CDDP-CRTX) and immune checkpoint inhibitor (ICI) monotherapy.Further detailed characterization of the tumor immune-micromilieu and its influence Milk Alternatives o

Inverse grading deposits are commonly found in circulation and accumulation areas of Milk Alternatives high-speed and long-distance landslides.Due to its special structure of large particle size at the top and small at the bottom and strong permeability, the accumulation is highly susceptible to unstable failure.In this study, using a self-designed

The global increase in cancer mortality and economic losses necessitates the cautious quest for therapeutic agents with compensatory advantages over conventional therapies.Anticancer peptides Slotted Spoon (ACPs) are a subset of host defense peptides, also known as antimicrobial peptides, which have emerged as therapeutic and diagnostic candidates

Objectives.Although hereditary neuropathy with liability to pressure palsies (HNPP) presents with a distinct phenotype on history, clinical exam, and nerve conduction studies, it may be masked if diagnostic work-up suggests other causes.Case Report.In a 37-year-old male with pseudoradicular lumbar pain, neurological exam revealed sore neck muscles,

Motolobalango and Madduta-Mamanu-manu customs in the courtship tradition of Gorontalo tribe and Bugis tribe have institutionalized in society.Motolobalango is carried out when the families of both parties have carried out dulohupa (meeting), while Madduta-Mamanu-manu is carried out when a boy proposes to a girl.These two customs have their own char